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Cosmetic Ingredient Skin Whitening Alpha Arbutin CAS 84380 01 8 4- Hydroquinone - Alpha -D- Glucopyranosid

Categories Natural Cosmetic Ingredients
Brand Name: Phytocare
Place of Origin: China
MOQ: Negotiation
Price: Negotiation
Payment Terms: L/C, D/A, D/P, T/T,PAYPAL
Supply Ability: 1000kg/month
Packaging Details: 25kg/bag
Name: Alpha arbutin
Chemical Name: 4-Hydroquinone-alpha-D-glucopyranosid
Specification: 99.5%
Application: Cosmetic for skin whitening
Grade: Cosmetic
Color: white
CAS No.: 84380-01-8
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    Cosmetic Ingredient Skin Whitening Alpha Arbutin CAS 84380 01 8 4- Hydroquinone - Alpha -D- Glucopyranosid

    Cosmetic Ingredient Whitening Alpha arbutin CAS No. 84380 01 8 4-Hydroquinone-alpha-D-glucopyranosid


    CAS No.: 84380-01-8

    Molecular Formula: C12H16O7

    Molecular Weight: 272.26

    Specification: ≥99.5%

    α-arbutin:α-arbutin:(Alpha Arbutin) is a new type of hydroquinone glucoside with an

    α-glucosyl bond.

    Arbutin is commercially used as a skin-whitening agent in cosmetic industry. It works by competitive inhibition of the enzyme, tyrosinase, a key enzyme in the synthesis of melanin.

    Depending on the spatial structure of the glycosidic linkage between glucose and hydroquinone, arbutin forms two epimers: Alpha Arbutin and Beta arbutin.

    Alpha Arbutin is enzymatically synthesized from hydroquinone and saccharides through transglycosylation reaction. Various carbohydrate-active enzymes such as α-amylase, α-glucosidase, transglucosidase, sucrose phosphorylase, and dextransucrase have been employed to synthesize Alpha Arbutin. It is one of the most advanced skin lightening ingredients on the market.

    Recent research showed that Alpha-Arbutin has a 10-fold stronger inhibitory effect on the activity of tyrosinase from human malignant melanoma cells than that of Beta-Arbutin. The α-glucosidic bond found in Alpha-Arbutin offers higher stability than the β form found in the related Beta-Arbutin. Moreover, Alpha-Arbutin hardly inhibited cell growth at 1 mmol/L, while Beta-Arbutin inhibit it significantly at the same concentration. It is, therefore, considered that Alpha-Arbutin is an effective and safe ingredient for cosmetics. Alpha arbutin is very expensive. That is the one downside.

    Skin whitening

    Arbutin exhibits potent melanin-inhibiting properties and confers whitening effects on the skin. Sun damage and injury or inflammation to the skin from acne, eczema or psoriasis are the two main factors that cause melanin production on the skin. Arbutin can reduce the accumulation of pigment by inhibiting the production of melanin, which accumulates on the skin when tyrosine is oxidized. An enzyme called tyrosinase is the catalytic for this reaction. Scientists found arbutin has shown inhibitory actions against tyrosinase. When topically apply skincare products containing Arbutin, the inhabitation of tyrosinase results in the decrease of melanin, thus, a whiter complexion.

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    Quality Cosmetic Ingredient Skin Whitening Alpha Arbutin CAS 84380 01 8 4- Hydroquinone - Alpha -D- Glucopyranosid for sale
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